With a new study, researchers aimed to examine the
association between age at menarche and gestational
diabetes mellitus (GDM).
Data were from 4,749 women participating in the
Australian Longitudinal Study on Women's Health
between 2000 and 2012.
Age at menarche was reported at baseline in 2000
when women were aged 22–27 years.
During 12 years of follow-up, information on GDM
diagnosis was obtained for each live birth.
Log-binomial regression analysis was used to
estimate relative risks and 95% confidence
Analyses adjusted for mother's highest completed
educational qualification, nulliparity, polycystic
ovary syndrome, physical activity, and body mass
Mean age at menarche was 12.9 years (standard
A first diagnosis of GDM was reported by 357 women
Compared with women with menarche at age 13 years,
women who had their first menstruation at age =11
years had a 51% higher risk of developing GDM (95%
confidence interval: 1.10, 2.07) after adjustment
for GDM risk factors.
Further prospective studies are needed.
Women’s age at first menstrual cycle linked to heart
disease risk (2014-12-17)
Starting periods before the age of 10 increases risk
of lung complaints in future (06/04/2011)
Puberty timing influenced by pubertal timing of both
For more information
Association Between Age at Menarche and Gestational
Diabetes Mellitus: The Australian Longitudinal Study
on Women's Health